Publication
Carbone CB, Kern N, Fernandes RA, Hui E, Su X, Garcia KC, Vale RD.
In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.
Proceedings of National Academy of Sciences U S A. 2017 Oct 31;114(44):E9338-E9345. Article
Arellano-Santoyo H, Geyer EA, Stokasimov E, Chen GY, Su X, Hancock W, Rice LM, Pellman D.
A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase Activity.
Developmental Cell. 2017 Jul 10;42(1):37-51. Article
Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD.
T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.
Science. 2017 Mar 31;355(6332):1428-1433. Article
Comment: Costimulation, a surprising connection for immunotherapy. [Science. 2017]
Highlight: Successful checkpoint blockade requires positive co-stimulation. [Nature Reviews Immunology. 2017]
Su X, Ditlev JA, Rosen MK, Vale RD.
Reconstitution of TCR Signaling Using Supported Lipid Bilayers.
Methods in Molecular Biology. 2017;1584:65-76. Article
Su X*, Ditlev JA*, Hui E, Xing W, Banjade S, Okrut J, King DS, Taunton J, Rosen MK**, and Vale RD**.
Phase separation of signaling molecules promotes T cell receptor signal transduction
Science. 2016 Apr; 352(6285):595-9. (*Co-first author, **Co-corresponding author) Article
Comment: Liquidity in immune cell signaling. [Science. 2016]
Report: Building Immunity: Team Recreates a T-Cell Receptor Signaling Pathway. [Science Daily. 2016]
Su X, Arellano-Santoyo H, Portran D, Gaillard J, Vantard M, Thery M, and Pellman D.
Microtubule sliding activity of a kinesin-8 promotes spindle assembly and spindle length control.
Nature Cell Biology. 2013 Aug; 15(8): 948-57. Article
Su X, Ohi R, Pellman D.
Move in for the kill: motile microtubule regulators (Review).
Trends in Cell Biology. 2012 Nov;22(11):567-75. Article
Su X, Qiu W, Gupta ML Jr, Pereira-Leal JB, Reck-Peterson SL, Pellman D.
Mechanisms underlying the dual-mode regulation of microtubule dynamics by kip3/kinesin-8.
Molecular Cell. 2011 Sep 2;43(5):751-63. Article
Wang Q, Teng J, Shen B, Zhang W, Guo Y, Su X, Zhang C, Yu AC, Chen J.
Characterization of kinesin-like proteins in silkworm posterior silk gland cells.
Cell Research. 2010 Jun;20(6):713-27. Article