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Xiaolei Su, PhD

Principal Investigator

Dr. Xiaolei Su obtained his B.S. at Peking University, Ph.D. at Harvard University, and postdoc training at UCSF. As a faculty at Yale, Dr. Su leads a team studying membrane signaling in immune responses.

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Jianjian Guo

Graduate Student

  • B.A. in Life Sciences from the University of Science and Technology of China

  • Studied CRISPR knock out screen in search for novel T cell immune suppressor against cancer at Yale for graduation thesis

  • Currently developing novel cell therapy against solid tumors in the Su Lab

  • Enjoys Sci-fi, psychology, movies, and pop music

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Fawzaan Hashmi

Research Assistant 

  • Yale College '25 with a major in Molecular, Cellular, and Developmental Biology

  • Yale First-Year Summer Research Fellowship

  • Prior work on cancer diagnostics and CRISPR-related ethics

  • Project: targeting tumor-associated myeloid cells with CAR-T

  • Enjoys traveling and rooting for LeBron

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Elahe Kamali, PhD

Postdoctoral Associate

  • Ph.D from the University of Isfahan

  • Worked on CRISPR/Cas9-based gene editing of human primary T cells and also involved in establishing a CRISPR-based assay (CRISPR-Select) to evaluate the possible driver role of cancer-associated mutations and predict treatment response

  • Joined the Su lab in May 2022 to explore the cell biology of CAR signaling and improve the CAR-T efficacy using genome editing.

  • Enjoys traveling, cycling, watching movies, and spending time with family and friends

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Yiwei Xiong, PhD

Postdoctoral Associate

  • Ph.D from the University of Liverpool on the roles of immune adaptor proteins in T-cells and macrophages

  • Studies immune signaling and cancer immunotherapy in the Su Lab

  • Enjoys soccer (avid Manchester United fan), beer, and traveling

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Kazuki Sato, PhD

Postdoctoral Fellow

  • Ph.D. from the University of Tsukuba, Japan in 2017 on the functional analysis of regulatory T cells

  • Daiichi Sankyo Foundation of Life Science Fellowship.

  • Joined the Su Lab in April 2022 studying the molecular mechanisms of immune cell activation and migration via phase separation

  • Enjoys cooking and making sweets with his family

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Xinyan Zhang, PhD

     Postdoctoral Fellow

  • Ph.D in pediatrics in 2017 from Tongji Medical College of Huazhong University of Science and Technology

  • Supported by the Leslie Warner Fellowship

  • Research in improving CAR-T sensitivity to target low-antigen expressing cancers and uncovering CAR-T signaling mechanism

  • Obsessed with translating new CARs to clinical medicine

  • Enjoys reading and running

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Longhui Zeng, PhD

Postdoctoral Fellow

  • Ph.D. in biology from Shanghai Jiao Tong University

  • Supported by the Cancer Research Institute Irvington Postdoc Fellowship

  • Studies how phase separation orchestrates immune signal transduction

  • Enjoys fishing, swimming, & listening to powerful and positive music